Research is the main activity of the IMO Foundation. By combining basic research and clinical research, and through an unique model where geneticists and ophthalmologists work together, we seek the progress of ophthalmology in order to find a solution to ocular pathologies for which there is still no cure.
Research in IMO
The IMO is at the forefront of research into the latest developments and contributes to the main clinical trials of the day as a member of the EVICR (European Vision Institute Clinical Research Network). The IMO’s leadership and innovative approach are also reflected in a unique and pioneering commitment to translational research, in which ophthalmologists and geneticists work side by side to advance faster in the prevention, diagnosis and treatment of hereditary eye diseases.
Ongoing projects
On this page you will find the ongoing projects that IMO Foundation is currently developing.
In the field of clinical research, the aim of the projects currently under development is not only to continue improving the prognosis of patients with certain pathologies, but also to offer, for the first time, effective solutions to diseases that currently have no treatment. This is also the ultimate goal of the basic research projects, which aim to analyze in depth already known genes, as well as to identify new genes related to hereditary eye diseases.
Investigación básica
Identification of new retinal dystrophies genes and characterization of genotype-phenotype correlations
The aim of this research project is to identify new causative genes of retinal dystrophies, in order to contribute to the knowledge and diagnosis of these diseases.
Investigación clínica
Thealoz Duo
Evaluation of Ocular Surface Disease Syntoms and Patients Satisfaction with Thealoz Duo after 84 days of Daily treatment
Investigación clínica
KOWA
A Double-Masked, Randomised, Placebo-Controlled, Parallel-Group, 12-Week, Phase 2 Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Descematorhexis in Patients with Fuchs Endothelial Corneal Dystrophy
Project history
On this page you will find the project history that the IMO Foundation has developed since its inception.
IMO's ophthalmologists, optometrists and nurses who specialise in ocular photography conduct several multi-centre clinical trials each year. These studies are in addition to the basic research projects pioneered by the Molecular Biology Laboratory.
Investigación básica
Mass sequencing of exomes for the identification of new genes and variants responsible for retinal dystrophies
Retinitis pigmentosa, with a prevalence of 1 in 4,000 people and more than one million sufferers worldwide, is the most common retinal dystrophy. These diseases are neurodegenerative and caused by the death of the photoreceptors and cells of the retinal pigment epithelium.
Investigación clínica
Duoprost
Phase III: Assessment of the efficacy and safety of a fixed combination of unpreserved latanoprost drops and timolol 0.5% (T2347) versus Xalacom® in patients with ocular hypertension or glaucoma.
