Research in IMO
Ongoing projects
Comprehensive analysis of the ABCA4 gene: characterization of new pathogenic variants
A great number of patients affected by retinal dystrophies with macular involvement, such as Stargardt's disease, have mutations in ABCA4, a complex and large gene. The aim of this research is to study this gene to improve the diagnosis and treatment of these pathologies.
XPLORE
A Phase III Double-Blind, Parallel Group, Multicenter Study to Compare the Efficacy and Safety of Xlucane versus Lucentis in Patients with Neovascular Age-Related Macular Degeneration
IN-SIGHT
Efficacy and safety assessment of T4032 (unpreserved bimatoprost 0.01%) versus Lumigan 0.01% in ocular hypertensiove or glacomatous patients
Project history
Mass sequencing of exomes for the identification of new genes and variants responsible for retinal dystrophies
Retinitis pigmentosa, with a prevalence of 1 in 4,000 people and more than one million sufferers worldwide, is the most common retinal dystrophy. These diseases are neurodegenerative and caused by the death of the photoreceptors and cells of the retinal pigment epithelium.
IRIS II
Compensation for blindness with the Intelligent Retinal Implant System (IRIS V2) in patients with retinal dystrophy.